Jerry Springer's frenzied audience greets Jerry as he arrives at his notorious TV talk show. His first guest, Dwight, is cheating on Peaches with Zandra. The three fight, and Jerry's security men break up the battle. Jerry is briefly admonished by his inner Valkyrie. Dwight is also cheating with a transexual, Tremont. After a commercial break, Jerry's second guest, Montel, tells his partner, Andrea, that he likes to dress as a baby and that he is cheating on her with Baby Jane, a woman who dresses as a little girl. Jerry's Warm-Up Man contributes to Andrea's humiliation and is fired. Jerry again wrestles with his inner Valkyrie. Jerry's final guests are Shawntel and her husband, Chucky. She wants to be a stripper and demonstrates a dance before her mother, Irene, arrives. Irene attacks Shawntel. Chucky pleads innocence, but Jerry's secret JerryCam camera footage shows that Chucky is a patron of strip clubs and a Ku Klux Klan member. The Klan comes up on stage, and the Warm Up Man gives Montel a gun. The Warm-Up Man jostles Montel, who accidentally shoots Jerry.
Jerry is found injured in a wheelchair, accompanied by his security man, Steve. The scene is Purgatory, a fog enshrouded wilderness. Jerry meets ghostly versions of his talk show guests, who have all suffered unpleasant fates. Jerry tries to justify his actions to the ghosts. The Warm-Up Man arrives and is revealed to be Satan. Baby Jane asks Satan to spare Jerry's soul. Satan forces Jerry to return to Hell with him to do a special show.
Jerry arrives in Hell at a charred version of his Earthly TV studio. The audience is locked into cracks in its walls. Jerry reads cue cards produced by Baby Jane that introduce Satan, who is in charge of the proceedings. Satan seeks an apology for his expulsion from Heaven and wants to reunite Heaven and Hell. Jerry must faithfully read the cue cards, which introduce Jesus, the next guest, who resembles Montel. Jesus and Satan trade accusations. Adam and Eve are next; they are reminiscent of Chucky and Shawntel. They argue with Jesus, and Eve eventually attacks him. Mary, mother of Jesus, who resembles Irene, condemns Jesus. Everyone turns against Jerry, who hopes for a miracle.
God and the angels arrive and ask Jerry to come to Heaven and help God judge Humanity. He accepts the offer, but the angels and devils fight over Jerry; and the talk-show host finds himself suspended over a pit of flame. Jerry launches into a series of glib homilies asking for his life, but finally gives up and makes an honest statement that resounds with his audience. Devils, angels, and everyone sing a hymn of praise to life.
Back on solid ground, Baby Jane tells Jerry that he must go back to Earth. Jerry wakes up in his television studio, having been shot, his life ebbing away as he is cradled in Steve's arms. Jerry gives a final speech, and everyone is joined in sorrow.